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Recent news - DiabetesHow Does Pain Etiology Influence Treatment Selection in Patients With Chronic Pain?diabetes news At the end of the study, a significantly greater percentage of patients receiving aliskiren/hydrochlorothiazide achieved the blood pressure goal of 130/80 mmHg compared with amlodipine (23.2% vs 13.8%; P .0001).Both treatments were generally well tolerated.

The overall rate of adverse events was 48.3% with amlodipine monotherapy and 36.0% with the combination therapy, and the majority of adverse events were mild to moderate in intensity.Peripheral oedema was more frequent with amlodipine than with aliskiren/hydrochlorothiazide (16.2% vs 2.1%).Funding for this study was provided by Novartis.[Presentation title: Initial Combination Therapy With Aliskiren and Hydrochlorothiazide is More Effective Than Amlodipine in Patients With Stage 2 Systolic Hypertension and Diabetes Mellitus..

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